Ah, a realistic shooter!
I long ago decided that I do NOT need to handload to "soup up" my guns--About the only ones I do that for are those for which the factories do not offer what I consider a suitable load for my needs--
.45 Colt, for many years, all you could get were 250 to 255 LRNFP bullets at levels safe for black powder era guns. Now, happily, there are some fairly brisk loads offered, but the main emphasis is still on the Cowboy Action loads, which are pretty anemic.
.44 Special - - similar to the .45 Colt loads--a 246 RNL at an optimistic 760 fps, while large bore, is too mild for hunting OR defense. Again, things have improved in the past 15 or so years, but my handloads are far better, though not screaming hot.
.257 Roberts used to be loaded only to very mild pressures.
Nowadays, I can buy good defensive ammo over the counter, so I load mainly to duplicate recoil and point of impact for the store-boughten stuff.
In .45 ACP - - -
230 FMJ with 6.5 gr. Unique pretty well duplicates the recoil and point of impact of the classic hardball .45.
230 LRN with about 6.2 Unique or 5.5 of W-231 does about the same thing. Actually, I load down to 5.3 of 231, which yields about 820 in a five-inch barrel. You have to shoot at pretty long range to tell the difference in POI between these loads and factory HydraShok or GDHP.
Good luck to you - - -
Johnny