Twenty five yards than 50 yards. This is the old NRA Bullseye Pistol distance, and if you want to get frustrated, try to keep them all in the ten ring, at 50 yards, with the NRA target. I can't, and I use two hands.
Real Bullseye Pistol shooters tell me of loads that are too wind sensitive at 50 yards, since I can't hold that hard, I will never know what the heck they are talking about. If I can hit a 12" gong at 50 yards, consistently, off hand, I consider the load good enough.