I don't subscribe to the wheel guns are better for girls idea. In fact, I don't subscribe to any particular pistol is better suited based on the dangly bits 'tween one's thighs.
You choose the best weapon based on tons of factors. Not a great shot? Get something with higher capacity. Are you going to carry? A wheelgun is generally harder to conceal. Want massive power? Can't really beat a .357 Magnum and that's only going to be in revolver.
Women are totally capable of handling semi automatics. They are no more complicated than kitchen appliances. The pros and cons should be illustrated, not "you're a woman. Get a revolver".