I have the 25-5 in .45 Colt (aka Long Colt) and it's an absolute joy to shoot and a wonder to handle. Heft, smooth, great lines, and a nice big push of recoil - and a nice BOOM vis a vis the hypersonic crack of the .357 Magnum - great gun.
Your 25-2 in .45ACP should also be a lot of fun. The big N-frame is a grin-maker in and of itself. It's the same frame as Dirty Harry's 29. You'll catch yourself standing in front of a mirror with a (triple-checked) empty gun, glaring, and with a clenched jaw doing the Dirty Harry, "Well, do you feel lucky PUNK?" And you'll have to smile because your 25's .45 caliber drills a bigger hole than Eastwood's .429.
Q