I sweat like a pig and work and play physically outdoors, all day, just about every day.
Kydex is the best thing since sliced light bread and will stop about 95% of your worries. It will also outlast any leather holster on the market. Blade Tech makes a great holster that will last about forever, and require basically no maintenance. The most you'll have to do, is replace a strap here or there if you use the straps. I was using the first Blade Tech I'd bought when I retired it and my Commander. The holster was used daily for ten years and still pretty much as good as new. I still have it and would not hesitate to use it.
Kydex is also more comfortable than leather, especially against wet skin, if that should happen. It will slide across your skin with out much annoyance, where wet leather will rub you raw, and the tanning chemicals just add to the misery.
I used to go through two, and sometimes three, good, brand name leather holsters a year. Most of the problem was the summer. Once a leather holster gets wet, it stays wet. Rough out leather is the worst, and absorbs quicker than smooth leather. Rough out horsehide isnt immune either. The last leather holsters I used for summer carry were Galco Royal Guards. They were good for about one day, then I had to buy another to try and rotate them out so one could dry. Didnt quite work that way, as they dont dry over night.
Here's that first Blade Tech (on the right) and the Commander that rode in it, with a new spare holster.
This was my last Royal Guard. (it sat in a "holster" box for years before I sold it on EBay) At the time I quit using it, it was about a month old. Duct tape on the back was an attempt to stop the sweat from getting through. Didnt work though.