Hmmmmm... what do I think? I think the Devil is in the details. Your execution is very well done, but it's the details that keep catching my attention:
I think the trigger needs to be straightened out just a tad.
I think the trigger and hammer would look better jeweled.
I LOVE the scales, though they look a little thick at the front for my taste
I like the polish line on the cylinder OK, but not the second one to hide the drag line... the timing should be fixed so that it doesn't scar the cylinder in the first place. Barring that, then forego the rear one altogether
I have never even thought of needing checkering on the back of a Bisley grip frame. I don't see any benefit but can think of several reasons not to.
I think the front sight base should match the finish of the barrel. Looks less 'added on' that way. Blalck sight blade is perfectly OK
The bead blasting looks very nice though I cannot say from this picture that it differs markedly from a stock Ruger finish.
I think that barrel rib looks completely out of place on a self described Saloon gun and a fat round or octagonal barrel would look much, much better.