My view: why go over 100-106 gr. in that caliber if the discussion is hunting? If you want heavier slower bullets there are other cartridges for that. The beauty of the 24's is light recoil, flat trajectories and hitting above its weight on game. The effectiveness of the 243 and 6mm has been a thing of joy for hunters for 65 years.
To answer your question:
I shoot, compete, varmint hunt, prairie dog hunt, and big game hunt differently than you do.
This is an assumption, but given your comments, it is an easy one to make.
Many of my specialty pistols are set-up for multi-tasking, as listed above.
The Achilles Heel of shooting distance is not drop, it is wind drift.
Drop is more of a given, than drift. Wind has a vertical feature as well, by itself, then when you add topography, even more so.
For the first time I used a 100 grain bullet in a 6mm to kill a pronghorn doe at 255 yards, because I had some old factory ammo I got with the 6mm BR XP-100, and I wanted to use it for fun on a lope. This is a old school slow twist barrel, so 100 grain (Corelokt) is much as I could use anyway.
Last year with a 15.75" XP in 6 Creed, I shot a lope at around a 1/4 mile. Wind is an issue where I live and hunt.
I usually confirm my drops to 1K on the majority of my specialty pistols, and sometimes out to about 1400-1500 yards.
I intentionally choose barrels and bullets that give me an advantage in both wind primarily and then in drop as well.
After you get out there, a bullet that may be heavier and start out slower, but it actually drops less than your lighter weight/faster bullets will. The light for caliber weight bullets shed velocity quickly, and drift quite a bit more than their heavier brothers and sisters.
Once I have my drops confirmed I typically begin practicing at 400 to 500 yards.
Sometimes I start on 10" steel at 300 just to check that nothing is off though.
"Flat trajectories" is just for a limited distance with lighter bullets.
If you are a short distance shooter/hunter, that is fine and I have no problem with that...to each his own.
Downrange ballistics is a whole different ball game, and I enjoy playing at distance. with 22lr's, revolvers, and specialty pistols. Rifles are kind of boring for me, but I do have them and use them occasionally.
Sorry to the OP for major thread-drift, but the discussion has been good.