The Underwood 185gr moving at 1200fps is pretty tempting.
I have the PX4 Compact in .40 that is my EDC. Awesome pistol. The full size PX4 in .45 should eat +P without a problem. Though, read the owners manual, just in case.
I'm creating safe pressure Longshot .40 180gr loads that are moving around 1190fps. 12+1 rounds of lite 10mm velocities. Awesome to say the least. PX4 eats them like candy.