Just looking at your last few posts without re quoting them here...
I don't know what the CUP on their hot handloaded 45LC is, and to be honest, if I did, I don't think I would post them on the web. If that is something you are interested in, I recommend you study several good relaoding manuals and work up your own load very carefully, starting low and slowly increasing.
If durability and reliability are your priority, as it is with me, as it should be with all shooters, then Ruger is your definite go to gun and then you just have to decide which one, but any of the full size Ruger revolvers are going to out live you.
If you think you want a revolver to fend off bears, you need to be looking at 44 magnum as opposed 357. A 357 in a rifle might suffice for smaller black bears but that's the reasonable limit. I would only use a 357 on a large bear if it was all I had. (And for a few years, I carried a 357 rifle because it was all I had.0
SO...if you're going to go 44, you should be looking at any of the "Hawk" guns in either SA or DA. The Super Redhawk is probably the strongest of them all. For bears, you need to be shooting the hard cast WFN type bullets, regardless of caliber. Penetration is the name of the game. PD rounds and JHP type ammo dumps all its energy quickly and never penetrates enough to actually hit any vital organs. For commercial stuff, look at the HSM bear loads in 180 grn for 357 and 305 grn in 44 magnum.
One final remark, the Ruger Redhawk and Super Redhawk are perennial favorites up here and for a good reason. They get the job done, last forever with zero maintenance other than cleaning, are dependable to the bitter end, and don't cost an arm and a leg. (So I don't cry if I drop it in the creek.)