One of my standard lines is "The round ball is effective all out of proportion to its size". I'm not generally a fan of energy figures for any bullet. That's especially true for handguns, and especially true for percussion revolvers. A .45 caliber round ball at reasonable velocity is adequate for anything up to 500 pounds at least, and energy figures be damned.
Indeed, though what I see is that having a bullet of similar weight traveling at a similar speed gives one an idea of capabilities. My NMA is virtually an uncased.45 Schofield and my ROA is virtually the original .45 Colt load with a lighter bullet. And when put in this light or perspective it provides the evidence that these aren’t the weak things I was told they were when I got my ROA and noticed it was the size of a .45 Colt. I was told that at best it was a .38 Spl and wasn’t humane to hunt with. Not so.