While the Ruger and Buckmark are definetly the major players I went with a S&W 422 as well and have no regrets or pistol envy at all.
I've shot likely 2500 to 3000 rounds out of it in the year and a bit I've owned it and IF it has failed me it was so long ago and seldom that I don't remember. Oh wait. I have to clean it about every 800 rounds or yes it does start to fail on me. But even then if I just scrape out the slide channels and oil it I can squeak out another 4 to 500 before it gets so grotty that I feel guilty and do a full strip and clean.
It's gobbled up and spit out Federal and Winchester bulk ammo, Blazer, Velocitor, two types of American Eagle, those Small Game Bullets that some brand makes and a few other higher velocity ammos without issue. The one thing it does not like is CCI Standard Velocity or anything at all subsonic. That ammo did cause some issues with stovepipes and similar woes.
The S&W 422 has a shiney stainless brother called the 2206. And both of these guns can use either their own mags or, with a very small mod to the slot that catches onto the mag catch, the ones from the S&W Model 41. So additional mags are not an issue.
As for accuracy it's not something an Olympic class bullseye shooter would use but it's far more accurate than my older guy eyeballs and nerves can hold onto. When I really concentrate it produces really first class groups. When I tried it rested it shot a big ragged hole for 10 shots at 12'ish yards. It's likely better than even that but I've still bot the old guy fuzzy eyes syndrome so I'm convinced that this thing is far, far better than me.
The 422 also has a really nice balance in the hand. And it's light on the hip for carrying where allowed. The light weight plays against me when I use it in our local Speed Steel matches but it's a very small disadvantage and for the most part I enjoy the slightly additional recoil over the much heavier Ruger or Buckmark options.
For looks it's a simple looking but pleasant appearing design. It is also very thin. And for the 422 version the main frame is alloy which greatly contributes to the lightweight feel on the hip if you were wanting to carry this in the bush. If there is a weak point on the appearance it's the plain looking wood grips. One day soon I'm going to coblle up some slick looking and checkered custom jobs to show my beloved 422 that she is appreciated. And when I do it won't take a back seat in appearance to any gun out there.
Sorry to prattle on at this length but I thought I'd add some support to the 422 post above to show that there's a lot of us very happy 422 owners out here.
And in fact thinking about the stainless 2206 option I realize now that the added weight of the stainless frame and slide would give me the added stability and low recoil to meet those other Ruger and Buckmark owners in the Speed Steel matches on common ground. And I've already got 5 mags to use along with any that would come with the 2206. Hmmmm..... Time to keep an eye open for another .22....