I'm glad you said that.
Best choices for self defense.
9mm, 357 Sig, 40, 45,10mm
Marginal choice for self defense,
as in we only carry it discontentedly in a NPE or when we can't do better. (hint: can't and won't aint the same)
380
Suitable for SD but the platform that fires them is capacity deficient, revolvers.
38 special, 357 Mag, 44, 50
(I may have omitted some like 41, but it doesn't matter)
Calibers that are deficient for self defense.
22, 25, 32
(James Bond and/or they carried 32 in Europe are irrelevant)
Disclaimers:
Yes if someone if frail, weak, then a 22,25,32 is "better than nothing" I get it, but "better than nothing" is not a goal for most.
If you like your revolver, fine, doesn't affect me, but it is capacity deficient compared to a 10+ round semi and statistics nor location change that.
If one is uncomfortable or incompetent with loaded chamber carry in a semi, they probably better off with a revolver, said by someone who obviously doesn't prefer them.
Infrequent shooters and novices are also probably best served by a revolver.