All of our HD weapons have cans in them. So does just about everything else except for revolvers and milsurps.
As for any perceived legal reason not to, unless the can itself is contraband, not something I'd worry about. Perception could matter if we were talking self defense claims in public with a carry gun, but that's a more difficult affirmative defense for many reasons. In your dwelling, the prerequistes for using deadly force against an intruder are far, far less stringent in most places in the U.S., and unlike the extra effort and considerations that would go into carrying a suppressed weapon on your person that may be considered in the same way as extra weapons or other things which might be perceived as excessive, construed as looking for a fight , there's no case to be made for that in a home defense situation where you would not be encumbered by it and obviously aren't seeking conflict in your own home. To the contrary, it's east to point out that you were protecting yourself and family from harm, including hearing damage.
IMO, the only legal liability consideration that matters in selecting a home defense weapon or ammo is over-penetration, a round leaving the structure.