Yep, we're running two different S&W 22a variants at the UT Austin campus range, and very pleased with them.
They're the most affordable .22 pistols in our collection, and have been running like champs. Our Browning is finnicky, not sure if it's fluke or the nature of Buckmarks. Our Rugers run great overall, but start light-striking when they get really grungy.
As odd as it sounds, the market-newcomer plastic pistol runs the best out of the three manufacturers. It does need to have the little plastic buffer replaced every few thousand rounds, but it's a 20c part from S&W. It breaks down far, far easier than the Buckmark or MkII/MkIII, to the great joy of our apprentice gunsmiths.
The grip angle is good, the lighter weight is pleasant, and they come in a wide variety of variants. Kids like the softer grip and the swoopy/modern aesthetic.
Two main complaints: 1) the magazines are more fragile that the Ruger ones, due to the chintyz baseplate. 2) the mag release is on the front-strap, not really a problem per se, but an odd quirk. Threw me for a real loop the first time I tried to unload one.
If you have any particular questions, feel free to post them here, and I'll glance back later.
-MV