I am almost exclusively a handgun hunter and when your chosen sidearm "generates" (actually, calculates is more accurate a term) well under what is considered by some a minimum for much African game, you learn to accept the fact that those numbers don't reveal much. I have killed water buffalo in the 2,000-lb range with the "inferior ballistics," quite convincingly, and am only glad that most bovines don't read well or they might find out on these forums that they shouldn't be dead.
I'll have to remind you that "superior" doesn't imply anything else is, or even might be inferior. Bison was almost wiped out from the face of the earth with black power loads, mainly old school .45-70. Back in the 1950's WWII parabellum, often in 7.65x21mm was a common hunting pistol for game of any size, including moose (which drove legislators to pass a very stringent hunting legislation for the time). Even Mossad has regarded .22lr as lethal against human targets for quite some time.
It's not about doing something. It's about overdoing it in a very practical manner, without drawbacks to speak of. If they are equivalent to bothering to learn how to reload shotshells and developing your own specialty loads, spending fifteen bucks on the latest edition of "Slug Loading Manual", a couple of hundred more on Lee Load-All 2 press, slug molds, casting equipment and shells/primers/powder, it's a matter of bothering to do it in the first place. Handloading isn't for everybody but as we all know, it opens a world of possibilities that otherwise aren't catered for by the market.
Like I've mentioned elsewhere, .45ACP, .44Spl and some other heavy(ish), already subsonic factory loads are the easiest way for a careful hunter to take suppressed yet ethical close range shots at medium game. 12" of penetration and large diameter wound channel works great.
When you multiply the projectile weight by four, expanded wound channel diameter by three and penetration by 1.5, you get massively more killing power. To the tune of creating a primary wound channel - the most crucial factor in terminal factor once hydrodynamic shock is very limited - of well over an inch. Overall terminal ballistic performance is close to some 7mm/.30 magnums and there's an abundance of momentum, all/most of which is transferred to the target.
What's not to like. It's not a howitzer or a vehicle-mounted relic, it's just a normally recoiling, very quiet shotgun that's light enough to carry on field for extended periods of time. In my book, according to simple physical facts and a first-hand proof of concept with an externally suppressed shotgun, it's the ultimate suppressed weapon for big game hunting. And smaller game too for targets of opportunity, or even on purpose. "Too much" power for someone's personal taste or preference? Cast a lighter slug, problem solved. It carries and shoots just as well as a subsonic smaller caliber rifle, with no practical downsides.