There are some cases like the .348win that gain a lot of capacity and velocity when Ackley-ized but the .280 isn't really one of them. The reasons to go Ackley:
- A little bit of case capacity
- The sharper shoulder reduces case stretch pretty much to zero - great for the reloader
- The sharper shoulder improves headspacing for improved accuracy
- The straighter case wall substantially reduces bolt thrust which lets you safely run at a higher pressure in a typical action that is bolt thrust limited rather than hoop strength limited. I'd run 65KPSI with the .280 AI no question in any action that would take say the Nosler cartridges. This gets you velocity well in excess of some published data.
People always say Ackley's data was hot, and it was, but the whole point is that the cases were designed to be run hot.