Have done, still do, on occasion
In the mid-1970s, as a young deputy sheriff, my service sidearm was a .357 - - First a Highway Patrolman, then a pre-27, and later a model 19. I also owned the obligatory .38 snub, of course. For special details in plainclothes or sporting purposes, I often concealed a .357, and believe me, the M19 was a LOT more comfortable than the N-frames.
I really favored a .45 auto and that was my principal off duty carry.
When felling "retro," I used to carry a 1940's era S&W Military & Police in an old style FBI type holster. I fired it in qualifications a least once a year, and left some of the younger troops shaking their heads.
--You see that ol' *bleep* Guest with his wore-out wheel gun?
--Yeah, and the ol' *bleep* can SHOOT the dang thing, too.
Since retirement, I find myself carrying an alloy-framed .38 more and more. My best compromise between comfort, concealability, and efficiency is probably my Colt Cobra with the fairly unusual four-inch barrel. It only weighs about 16 ounces and packs nicely in an belt slide or in a lightweight shoulder holster. With the longer barrel, the sight radius makes it easy to shoot well, and there's significant added velocity over a two-inch Colt Agent or S&W M37.
Best
Johnny