Anyone who carries with no round in the chamber is wasting their time, and is carrying a gun for no reason. When it requires any explaining past the obvious it becomes an exercise in futility. I would certainlly ask anyone who has ever needed to use their gun, how that would have worked out for them if there was no round chambered.
Think about it this way, if you carried a revolver, "unless you carried a single action Colt back in the Wild West, would you have the hammer resting on a live round, or would you take a round out for the hammer to rest on?
Well if you wouldn't take out a round, why would you carry an unchambered semi-auto pistol?
Guns only fire when you pull the trigger, so if you don't trust yourself enough to not pull the trigger, why carry at all.
Any semiauto pistol that was made during your lifetime, is not going to suddenly go off by mistake, Most of us have fallen off roofs, ladders, had car accidents, plane crashes, etc, and never had a gun go off without pulling the darn trigger. You won't have time when the crap hits the fan, so if you carry an unloaded gun, just leave it home so someone dosen't take it away and shoot you with it.