Doc,
I am frankly not sure if your sticking up for the .22 or pointing out that it is in fact insufficient, but in the interest of supporting my own argument that it is not sufficient as a self defense round, let me mention a couple of observations that I got off of your supplied reading material. Let me make it clear that I am aware that you weren't challenging my points in particular, and that this response is to your data, not directed towards you personally.
1. Looking at the ballistics chart, the .22 is in no way, shape or form superior too, or even comparable to the more common self defense rounds. I will admit that I didn't look at every chart, but comparing the .22 between the 9mm, .45ACP, .357Mag and .223 rounds (which I view as being the most popular SD rounds) tells me that there isn't even a little bit of comparison between the two. That wasn't unexpected.
2. Reading the FBI report, you are correct in saying that the Patrick says that the .22 has killed more people than any other cartridge. However, to preface that, he also says that "body count is no evidence of incapacitation". Further, in his conclusion he states that "Psychologically, some individuals can be incapactated by minor or small caliber wounds". He further states that penetration is the key to incapacitation, but that the bullet must be of a large enough diameter. His final sentence probably is the one that supports my argument the best: "Of those that will penetrate, the edge is always with the bigger bullet".
My main point personally was that the .22 is unlikely to incapacitate the bad guy, a claim that he seems to support. I also said that it is better than nothing, a claim that he seems too at least validate. In any case, given that the goal of SD is to stop the threat (which is not necessesarily the same as killing the threat, but that point is really just semantics), the data you supplied seems to support my claim that the .22 is not sufficient to that task, at least most of the time. I would also point out that Patrick said, essentially, the same thing that I did when he stated that no caliber is guaranteed a one shot stop, unless you happen to hit the brain. He doesn't say this, but I know that given the right angle, the luck of the Irish, and the Hand of God, bullets can be and have been deflected off the skull. That certainly sucks for the person whose skull was doing the deflecting, but when your jacked up on adrenaline, you may or may not notice the pain, and in any case are not incapacitated, at least immediately.
If all I had on hand was a .22, I would use it and who knows, maybe I get lucky and stop the guy in his tracks. Looking at the data you supplied, that seems unlikely, and the guy dying an hour or so after he kills me and my family is very little solace.